• Users Online: 231
  • Print this page
  • Email this page
Year : 2016  |  Volume : 2  |  Issue : 3  |  Page : 90-93

Anticonvulsants and antidepressants in chronic pain management

1 Associate Professor and Pain Consultant, Department of Anesthesiology, BIRDEM General Hospital and Ibrahim Medical College, Dhaka, Bangladesh
2 Professor and Director, Department of Physical Medicine and Medical Education Directorate General of Health Services, Dhaka, Bangladesh
3 Pain Specialist and Head, Department of Anesthesiology, Northern International Medical College and Hospital, Dhaka, Bangladesh
4 Principal, Department of Anesthesiology, President Abdul Hamid Medical College & Hospital, Kishorganj, Bangladesh

Correspondence Address:
Kawsar Sardar
Associate Professor and Pain Consultant, Department of Anesthesiology, BIRDEM General Hospital and Ibrahim Medical College, Dhaka
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.5005/jp-journals-10046-0050

Rights and Permissions

Epidemiological studies have found that 10.1 to 55.2% of people in various countries have chronic pain. Various medicines are prescribed, depending on whether the pain originates from tissue damage or is neuropathic. Evidence suggests that chronic pain from tissue inflammation or damage as in rheumatoid arthritis and cancer pain is best treated with opioids and anti-inflammatory drugs, while for neuropathic pain where pain is caused by a damaged or dysfunctional nervous system other drugs may be more effective. Chronic pain is a global concern affecting people from all walks of life. As the epidemic of opioid misuse continues to grow, the need for balanced, multimodal approaches to the treatment of pain syndromes has become more apparent. These include medications which, though originally designed to treat other pathologies, have demonstrated benefits in the treatment of chronic pain. This article is a review of the pharmacodynamics of various classes of antidepressants and anticonvulsants and the effects of these drugs on pain signaling and perception. Finally, recommendations for the use of such drugs in the patient with chronic pain are discussed.

Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded77    
    Comments [Add]    
    Cited by others 3    

Recommend this journal