| REVIEW ARTICLE |
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| Year : 2020 | Volume
: 6
| Issue : 2 | Page : 1-4 |
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“Ozone” - A better alternative in COVID-19 pandemic
Khaja Javed Khan1, Gautam Das2
1 Alleviate Pain and Spine Clinic, Bengaluru, Karnataka, India
2 Daradia: The Pain Clinic, Kolkata, West Bengal, India
Correspondence Address:
Khaja Javed Khan
No. 10, 4th Main, K.R.Gardens, Murugeshpalya, Old Airport Road, Bengaluru - 560 017, Karnataka
India
 Source of Support: None, Conflict of Interest: None
DOI: 10.4103/jrap.jrap_2_20
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Ozone is a molecule consisting of three atoms of oxygen in a dynamically unstable structure. Ozone gas has been used in pain medicine practice for intraarticular injections, intradiscal, periforaminal or intraforaminal injections. Ozone is inherently bacteriostatic, fungicidal, and virucidal. The world is now facing one of the biggest crises known to humankind, the Coronavirus pandemic. This COVID-19 is multiplying at an unprecedented pace, affecting the population worldwide. Coronaviruses have abundant cysteine in their spike proteins that may be easily and safely exploited with ozone (or other oxidation) therapy. Cysteine residues are also abundant in viral membrane proteins and must be “conserved” for viral cell entry. Ozone has a unique ability to inactivate cysteine dependent proteins. Ozone injections in pain medicine have reported encouraging effects in pain control and functional recovery. All of these factors, coupled with the comparatively low cost of Ozone make it an attractive alternative option compared to platelet-rich plasma or steroid injections in the present COVID-19 pandemic crisis.
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